Almost every medical treatment has risks and side effects to it, which vary in degree from person to person. The benefit of oxygen therapy is that it is not a foreign drug, we naturally use it everyday and therefore the only side effects will be due to the administration of it or because of the volume of oxygen being inhaled, which as a result dramatically reduces side effects when compared to other medical treatments. There is also the safety aspect of storing and using oxygen as it is highly combustable but as long as you follow the simple common sense safety advice from your provider you will be very safe.
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The side effects may include a dry or bloody nose, skin irritation from the nasal cannula or face mask, fatigue, tiredness and morning headaches. Some people only suffer side effects initially upon first use and then they disappear however if these problems persist then all you need to do is to inform your doctor and provider. Depending upon the problems all your doctor may need to do is to alter the oxygen flow rate or length of time you’re using the equipment.
If nose dryness is a problem then you may just require an additional nasal spray or to have a humidifier attached to your equipment to reduce the dryness effect of the oxygen.
If you experience irritation from the mask or cannula then your provider can try other devices that may fit you better and can recommend over-the-counter gels and devices designed to help lessen skin irritation.
If you use transtracheal oxygen therapy then complications can potentially be a bit more serious due to the more invasive way that the oxygen is delivered via a tube inserted into your windpipe a the front of your neck. You may develop mucus balls which can cause coughing and clog the windpipe, infection and injury to the windpipe. However as long as you follow the advice in the proper medical care and correct handling of the tube then this greatly reduces the risk of complications. Such as keeping it clean and to use suction to remove any build-up.
The majority of users find that they experience a little irritation and dryness which can be easily resolved. Their testimonials are clear in saying that the benefits of oxygen therapy such as improved quality of life, improved mobility and social interaction and longevity of life far outweigh the inconvenience of a few side effects.
References: http://www.nhlbi.nih.gov and http://www.livestrong.com